Global DNA Methylation Market

1.1    Inclusion and Exclusion

2.1    Scope of Work
2.2    Key Questions Answered in the Report

3.1    Global DNA Methylation Market: Research Methodology
3.2    Data Sources
3.3    Secondary Data Sources
3.4    Market Estimation Model
3.5    Criteria for Company Profiling

4.1    Market Definition
4.2    DNA Methylation: Impact on Human Health
4.3    Market Size and Growth Potential, $Million, 2019-2030
4.4    Future Potential
4.5    COVID-19 Impact on the Global DNA Methylation Market

5.1    Overview
5.2    Legal Requirements and Framework in the U.S.
5.3    Legal Requirements and Framework in Europe
5.4    Legal Requirements and Framework in Asia-Pacific
         5.4.1    China
         5.4.2    Japan

6.1    Overview
6.2    Iceberg Analysis
6.3    Impact Analysis
6.4    Market Drivers
         6.4.1    Global Increase in Cancer Prevalence
         6.4.2    Increasing Government Funding for Healthcare
         6.4.3    Declining Costs and Increasing Output of Sequencing
6.5    Market Restraints
         6.5.1    High Cost of Instrument
         6.5.2    Lack of High-Complexity Testing Centers and Skilled Professionals in High-Growth Regions
         6.5.3    Low Adoption in Diagnostic Applications
6.6    Market Opportunities
         6.6.1    Growing Trend of Methylome Sequencing for Precision Medicine
         6.6.2    Advancing Technological Developments for Methylome Sequencing
         6.6.3    Growth in Non-Oncology Applications of DNA Methylation

7.1    Product Launches and Upgrades
7.2    Synergistic Activities
7.3    Acquisitions
7.4    Product Approvals, Business Expansion, and Other Activities
7.5    Market Share Analysis, 2018-2019
7.6    Growth Share Analysis
         7.6.1    Growth Share Analysis (by Company)
         7.6.2    Growth Share Analysis (by Technology)
         7.6.3    Growth Share Analysis (by Application)

8.1    Overview
8.2    Consumables
8.3    Instruments
8.4    Software

9.1    Overview
9.2    Polymerase Chain Reaction (PCR)
9.3    Sequencing
         9.3.1    Next-Generation Sequencing (NGS)
         9.3.2    Traditional Sequencing
9.4    Microarray
9.5    Other Technologies

10.1    Overview
10.2    Clinical Applications
10.3    Translational Research
           10.3.1    Oncology Research
           10.3.2    Non-Oncology Research
           10.3.3    Other Research Applications

11.1    Overview
11.2    Pharmaceutical and Biotechnology Companies
11.3    Research and Academic Institutions
11.4    Contract Research Organizations
11.5    Other End Users

12.1    Overview
12.2    North America
           12.2.1    U.S.
           12.2.2    Canada
           12.2.3    North America DNA Methylation Market (by Translational Research), 2019-2030
12.3    Europe
           12.3.1    Germany
           12.3.2    U.K.
           12.3.3    France
           12.3.4    Italy
           12.3.5    Spain
           12.3.6    Rest-of-Europe
           12.3.7    Europe DNA Methylation Market (by Translational Research), 2019-2030
12.4    Asia-Pacific
           12.4.1    China
           12.4.2    Japan
           12.4.3    India
           12.4.4    South Korea
           12.4.5    Australia
           12.4.6    Rest-of-APAC
           12.4.7    Asia-Pacific DNA Methylation Market (by Translational Research), 2019-2030
12.5    Latin America
           12.5.1    Brazil
           12.5.2    Mexico
           12.5.3    Rest-of-Latin America
           12.5.4    Latin America DNA Methylation Market (by Translational Research), 2019-2030
12.6    Rest-of-the-World

13.1    Overview
13.2    Abcam plc
           13.2.1    Company Overview
           13.2.2    Role of Abcam plc in the Global DNA Methylation Market
           13.2.3    Financials
           13.2.4    Key Insights About Financial Health of the Company
           13.2.5    SWOT Analysis
13.3    Active Motif, Inc.
           13.3.1    Company Overview
           13.3.2    Role of Active Motif, Inc. in the Global DNA Methylation Market
           13.3.3    SWOT Analysis
13.4    Agilent Technologies, Inc.
           13.4.1    Company Overview
           13.4.2    Role of Agilent Technologies, Inc. in the Global DNA Methylation Market
           13.4.3    Financials
           13.4.4    Key Insights About Financial Health of the Company
           13.4.5    SWOT Analysis
13.5    Bio-Rad Laboratories, Inc.
           13.5.1    Company Overview
           13.5.2    Role of Bio-Rad Laboratories, Inc. in the Global DNA Methylation Market
           13.5.3    Financials
           13.5.4    Key Insights About Financial Health of the Company
           13.5.5    SWOT Analysis
13.6    Diagenode Diagnostics S.A.
           13.6.1    Company Overview
           13.6.2    Role of Diagenode Diagnostics S.A. in the Global DNA Methylation Market
           13.6.3    SWOT Analysis
13.7    EpiGentek Group Inc.
           13.7.1    Company Overview
           13.7.2    Role of EpiGentek Group Inc. in the Global DNA Methylation Market
           13.7.3    SWOT Analysis
13.8    Exact Sciences Corporation
           13.8.1    Company Overview
           13.8.2    Role of Exact Sciences Corporation in the Global DNA Methylation Market
           13.8.3    Financials
           13.8.4    Key Insights About Financial Health of the Company
           13.8.5    SWOT Analysis
13.9    F. Hoffmann-La Roche Ltd.
           13.9.1    Company Overview
           13.9.2    Role of F. Hoffmann-La Roche Ltd in the Global DNA Methylation Market
           13.9.3    Financials
           13.9.4    Key Insights About Financial Health of the Company
           13.9.5    SWOT Analysis
13.10   Illumina, Inc.
            13.10.1    Company Overview
            13.10.2    Role of Illumina, Inc. in the Global DNA Methylation Market
            13.10.3    Financials
            13.10.4    Key Insights About Financial Health of the Company
            13.10.5    SWOT Analysis
13.11    Merck KGaA
            13.11.1    Company Overview
            13.11.2    Role of Merck KGaA in the Global DNA Methylation Market
            13.11.3    Financials
            13.11.4    Key Insights About Financial Health of the Company
            13.11.5    SWOT Analysis
13.12   New England Biolabs, Inc.
            13.12.1    Company Overview
            13.12.2    Role of New England Biolabs, Inc.  in the Global DNA Methylation Market
            13.12.3    SWOT Analysis
13.13   Pacific Biosciences of California, Inc.
            13.13.1    Company Overview
            13.13.2    Role of Pacific Biosciences of California, Inc. in the Global DNA Methylation Market
            13.13.3    Financials
            13.13.4    Key Insights About Financial Health of the Company
            13.13.5    SWOT Analysis
13.14   PerkinElmer, Inc.
            13.14.1    Company Overview
            13.14.2    Role of PerkinElmer, Inc. in the Global DNA Methylation Market
            13.14.3    Financials
            13.14.4    Key Insights About Financial Health of the Company
            13.14.5    SWOT Analysis
13.15   QIAGEN N.V.*
            13.15.1    Company Overview
            13.15.2    Role of QIAGEN N.V. in the Global DNA Methylation Market
            13.15.3    Financials
            13.15.4    Key Insights About Financial Health of the Company
            13.15.5    SWOT Analysis
13.16   Thermo Fisher Scientific Inc.
            13.16.1    Company Overview
            13.16.2    Role of Thermo Fisher Scientific Inc. in the Global DNA Methylation Market
            13.16.3    Financials
            13.16.4    Key Insights About Financial Health of the Company
            13.16.5    SWOT Analysis
13.17   Zymo Research Corporation
            13.17.1    Company Overview
            13.17.2    Role of Zymo Research Corporation in the Global DNA Methylation Market
            13.17.3    SWOT Analysis

Table 5.1:    Classification Rules of IVDs Under the IVDR
Table 5.2:    Registration Criteria for IVD Medical Devices as per the NMPA
Table 8.1:    Examples of Consumables in the Global DNA Methylation Market
Table 8.2:    Examples of Instruments in Global DNA Methylation Market
Table 8.3:    Examples of Software in the Global DNA Methylation Market

Figure 1:    Cancer Epigenetic Biomarker Publications Per Annum Vs. Cumulative Registered DNA Methylation-based In Vitro Diagnostics, 2010-2019
Figure 2:    Impact Analysis of Market Drivers and Market Challenges on the Global DNA Methylation Market
Figure 3:    Global DNA Methylation Market (by Product), 2019 vs. 2030 ($Million)
Figure 4:    Global DNA Methylation Market (by Technology), 2019 vs. 2030 ($Million)
Figure 5:    Global DNA Methylation Market (by Application), 2019 vs. 2030 ($Million)
Figure 6:    Global DNA Methylation Market (by End User), 2019 vs. 2030 ($Million)
Figure 7:    Global DNA Methylation Market Snapshot
Figure 2.1:    Global DNA Methylation Market Segmentation
Figure 3.1:    Global DNA Methylation Market Research Methodology
Figure 3.2:    Primary Research Methodology
Figure 3.3:    Bottom-Up Approach (Segment-Wise Analysis)
Figure 3.4:    Top-Down Approach (Segment-Wise Analysis)
Figure 4.1:    Global DNA Methylation Market, 2019-2030
Figure 4.2:    Global DNA Methylation Market: COVID-19 Impact
Figure 5.1:    Components Considered for Clinical Evidence as per the IVDR
Figure 5.2:    Medical Device Designation Process by MHLW and PMDA
Figure 6.1:    Iceberg Analysis – Global DNA Methylation Market
Figure 6.2:    Impact Analysis
Figure 6.3:    Global Cancer Burden, 2018
Figure 6.4:    Increasing Government Spending for Healthcare, 2017
Figure 6.5:    Decreasing Cost and Increasing Output (TB) of Genome Sequencing (2009-2025)
Figure 6.6:    Milestones for Clinical Implementation of a Candidate DNA Methylation Biomarker
Figure 6.7:    Evolution of NGS-Based Techniques Applied to DNA Methylation Profiling
Figure 7.1:    Share of Key Developments and Strategies, January 2017–May 2020
Figure 7.2:    Product Launches Share (by Company), January 2017–May 2020
Figure 7.3:    Synergistic Activities Share (by Company), January 2017–May 2020
Figure 7.4:    Share of Acquisitions (by Company), January 2016–February 2020
Figure 7.5:    Market Share Analysis for Global DNA Methylation Market, 2018 and 2019
Figure 7.6:    Growth Share Analysis for Global DNA Methylation Market (by Company), 2019
Figure 7.7:    Growth Share Analysis for Global DNA Methylation Market (by Technology), 2019-2030
Figure 7.8:    Growth Share Analysis for Global DNA Methylation Sequencing Market (by Application), 2019-2030
Figure 8.1:    Global DNA Methylation Market (by Product Type)
Figure 8.2:    Global DNA Methylation Market (by Product Type), 2019 and 2030
Figure 8.3:    Global DNA Methylation Market (by Consumable), 2019-2030
Figure 8.4:    Global DNA Methylation Market (by Consumable), 2019 and 2030
Figure 8.5:    Global DNA Methylation Market (Consumable, by Technology),  2019 and 2030
Figure 8.6:    Global DNA Methylation Market (by Instruments), 2019-2030
Figure 8.7:    Global DNA Methylation Market (Instrument, by Technology), 2019 and 2030
Figure 8.8:    Global DNA Methylation Market (by Software), 2019-2030
Figure 9.1:    Global DNA Methylation Market (by Technology)
Figure 9.2:    Global DNA Methylation Market (by Technology), 2019-2030
Figure 9.3:    Global DNA Methylation Market (by PCR), 2019-2030
Figure 9.4:    Evolution of Sequencing for Molecular Diagnostics
Figure 9.5:    Global DNA Methylation Market (by Sequencing), 2019 and 2030
Figure 9.6:    Global DNA Methylation Market (by NGS), 2019-2030
Figure 9.7:    Global DNA Methylation Market (by Traditional Sequencing), 2019-2030
Figure 9.8:    Global DNA Methylation Market (by Microarray), 2019-2030
Figure 9.9:    Global DNA Methylation Market (by Other Technologies), 2019-2030
Figure 10.1:    Global DNA Methylation Market (by Application)
Figure 10.2:    Global DNA Methylation Market (by Application), 2019-2030
Figure 10.3:    Global DNA Methylation Market (by Clinical Applications), 2019-2030
Figure 10.4:    Global DNA Methylation Market (by Translational Research), 2019 and 2030
Figure 10.5:    Global DNA Methylation Market (by Oncology Research), 2019-2030
Figure 10.6:    Global DNA Methylation Market (by Non-Oncology Research), 2019-2030
Figure 10.7:    Global DNA Methylation Market (by Non-Oncology Research),  2019 and 2030
Figure 10.8:    Global DNA Methylation Market (by Other Research Applications),  2019-2030
Figure 11.1:    Global DNA Methylation Market (by End User)
Figure 11.2:    Global DNA Methylation Market (by Pharmaceutical and Biotechnology Companies), 2019-2030
Figure 11.3:    Global DNA Methylation Market (by Research and Academic Institutions), 2019-2030
Figure 11.4:    Global DNA Methylation Market (by Contract Research Organizations), 2019-2030
Figure 11.5:    Global DNA Methylation Market (by Other End Users), 2019-2030
Figure 12.1:    Global DNA Methylation Market (by Region)
Figure 12.2:    Global DNA Methylation Market (by Region), 2019-2030
Figure 12.3:    North America DNA Methylation Market, 2019-2030
Figure 12.4:    North America: Market Dynamics
Figure 12.5:    North America DNA Methylation Market (by Country), 2019-2030
Figure 12.6:    U.S. DNA Methylation Market, 2019-2030
Figure 12.7:    Canada DNA Methylation Market, 2019-2030
Figure 12.8:    North America DNA Methylation Market (by Translational Research),  2019-2030
Figure 12.9:    Europe DNA Methylation Market, 2019-2030
Figure 12.10: Europe: Market Dynamics    
Figure 12.11: Europe DNA Methylation Market (by Country), 2019-2030    
Figure 12.12: Germany DNA Methylation Market, 2019-2030    
Figure 12.13: U.K. DNA Methylation Market, 2019-2030    
Figure 12.14: France DNA Methylation Market, 2019-2030    
Figure 12.15: Italy DNA Methylation Market, 2019-2030    
Figure 12.16: Spain DNA Methylation Market, 2019-2030    
Figure 12.17: Rest-of-Europe DNA Methylation Market, 2019-2030    
Figure 12.18: Europe DNA Methylation Market (by Translational Research), 2019-2030    
Figure 12.19: Asia-Pacific DNA Methylation Market, 2019-2030    
Figure 12.20:    APAC: Market Dynamics
Figure 12.21:    APAC DNA Methylation Market (by Country), 2019-2030
Figure 12.22:    China DNA Methylation Market, 2019-2030
Figure 12.23:    Japan DNA Methylation Market, 2019-2030
Figure 12.24:    India DNA Methylation Market, 2019-2030
Figure 12.25:    South Korea DNA Methylation Market, 2019-2030
Figure 12.26:    Australia DNA Methylation Market, 2019-2030
Figure 12.27:    RoAPAC DNA Methylation Market, 2019-2030
Figure 12.28:    Asia-Pacific DNA Methylation Market (by Translational Research), 2019-2030
Figure 12.29:    Latin America DNA Methylation Market, 2019-2030
Figure 12.30:    Latin America: Market Dynamics
Figure 12.31:    Latin America DNA Methylation Market (by Country), 2019-2030
Figure 12.32:    Brazil DNA Methylation Market, 2019-2030
Figure 12.33:    Mexico DNA Methylation Market, 2019-2030
Figure 12.34:    Rest-of-Latin America DNA Methylation Market, 2019-2030
Figure 12.35:    Latin America DNA Methylation Market (by Translational Research), 2019-2030
Figure 12.36:    RoW DNA Methylation Market, 2019-2030
Figure 13.1:    Total Number of Companies Profiled
Figure 13.2:    Abcam plc: Product Portfolio
Figure 13.3:    Abcam plc: Overall Financials, 2016-2018
Figure 13.4:    Abcam plc: Revenue (by Region), 2016-2018
Figure 13.5:    Abcam plc: R&D Expenditure, 2016-2018
Figure 13.6:    Abcam plc: SWOT Analysis
Figure 13.7:    Active Motif, Inc.: Product Portfolio
Figure 13.8:    Active Motif, Inc.: SWOT Analysis
Figure 13.9:    Agilent Technologies, Inc.: Product Portfolio
Figure 13.10:    Agilent Technologies, Inc.: Overall Financials, 2017-2019
Figure 13.11:    Agilent Technologies, Inc.: Revenue (by Segment), 2017-2019
Figure 13.12:    Agilent Technologies, Inc.: Revenue (by Region), 2017-2019
Figure 13.13:    Agilent Technologies, Inc.: R&D Expenditure, 2017-2019
Figure 13.14:    Agilent Technologies, Inc.: SWOT Analysis
Figure 13.15:    Bio-Rad Laboratories, Inc.: Portfolio
Figure 13.16:    Bio-Rad Laboratories, Inc.: Overall Financials, 2017-2019
Figure 13.17:    Bio-Rad Laboratories, Inc.: Revenue (by Segment), 2017-2019
Figure 13.18:    Bio-Rad Laboratories, Inc.: Revenue (by Region), 2017-2019
Figure 13.19:    Bio-Rad Laboratories, Inc.: R&D Expenditure, 2017-2019
Figure 13.20:    Bio-Rad Laboratories
Figure 13.21:    Diagenode Diagnostics S.A.: Product Portfolio
Figure 13.22:    Diagenode Diagnostics S.A.: SWOT Analysis
Figure 13.23:    EpiGentek Group Inc.: Product Portfolio
Figure 13.24:    EpiGentek Group Inc.: SWOT Analysis
Figure 13.25:    Exact Sciences Corporation: Portfolio
Figure 13.26:    Exact Sciences Corporation: Overall Financials, 2017-2019
Figure 13.27:    Exact Sciences Corporation: Revenue (by Segment), 2017-2019
Figure 13.28:    Exact Sciences Corporation: Revenue (by Region), 2017-2019
Figure 13.29:    Exact Sciences Corporation: R&D Expenditure, 2017-2019
Figure 13.30:    Exact Sciences Corporation
Figure 13.33:    F. Hoffmann-La Roche Ltd: Sales (by Segment), 2017-2019
Figure 13.34:    F. Hoffmann-La Roche Ltd: Sales (by Region), 2017-2019
Figure 13.35:    F. Hoffmann-La Roche Ltd: R&D Expenditure, 2017-2019
Figure 13.36:    F. Hoffmann-La Roche: SWOT Analysis
Figure 13.37:    Illumina, Inc.: Product Portfolio
Figure 13.38:    Illumina, Inc.: Overall Financials, 2017-2019
Figure 13.39:    Illumina, Inc.: Revenue (by Segment), 2017-2019
Figure 13.40:    Illumina, Inc.: Revenue (by Region), 2016-2018
Figure 13.41:    Illumina, Inc.: R&D Expenditure, 2016-2018
Figure 13.42:    Illumina, Inc.: SWOT Analysis
Figure 13.43:    Merck KGaA: Overall Product Portfolio
Figure 13.44:    Merck KGaA: Overall Financials, 2017-2019
Figure 13.45:    Merck KGaA: Revenue (by Segment), 2017-2019
Figure 13.46:    Merck KGaA: Revenue (by Region), 2017-2019
Figure 13.47:    Merck KGaA: Life Science Segment Revenue (by Region), 2017-2019
Figure 13.48:    Merck KGaA: R&D Expenditure, 2016-2018
Figure 13.49:    Merck KGaA: SWOT Analysis
Figure 13.50:    New England Biolabs, Inc.: Product Portfolio
Figure 13.51:    New England Biolabs, Inc.: SWOT Analysis
Figure 13.52:    Pacific Biosciences of California, Inc.: Overall Product Portfolio
Figure 13.53:    Pacific Biosciences of California, Inc.: Overall Financials, 2017-2019
Figure 13.54:    Pacific Biosciences of California, Inc.: Revenue (by Segment), 2017-2019
Figure 13.55:    Pacific Biosciences of California, Inc.: Revenue (by Region), 2017-2019
Figure 13.56:    Pacific Biosciences of California, Inc.: R&D Expenditure, 2017-2019
Figure 13.57:    Pacific Biosciences of California, Inc.: SWOT Analysis
Figure 13.58:    PerkinElmer, Inc.: Portfolio
Figure 13.59:    PerkinElmer, Inc.: Overall Financials, 2017-2019
Figure 13.60:    PerkinElmer, Inc.: Revenue (by Segment), 2017-2019
Figure 13.61:    PerkinElmer, Inc.: Revenue (by Region), 2017-2019
Figure 13.62:    PerkinElmer, Inc.: R&D Expenditure, 2017-2019
Figure 13.63:    PerkinElmer, Inc.: SWOT Analysis
Figure 13.64:    QIAGEN N.V.: Portfolio
Figure 13.65:    QIAGEN N.V.: Overall Financials, 2017-2019
Figure 13.66:    QIAGEN N.V.: Revenue (by Segment), 2017-2019
Figure 13.67:    QIAGEN N.V.: Revenue (by Region), 2017-2019
Figure 13.68:    QIAGEN N.V.: R&D Expenditure, 2017-2019
Figure 13.69:    QIAGEN N.V.: SWOT Analysis
Figure 13.70:    Thermo Fisher Scientific Inc.: Product Portfolio
Figure 13.71:    Thermo Fisher Scientific Inc.: Overall Financials, 2017-2019
Figure 13.72:    Thermo Fisher Scientific Inc.: Revenue (by Segment), 2017-2019
Figure 13.73:    Thermo Fisher Scientific Inc.: Revenue (by Region), 2017-2019
Figure 13.74:    Thermo Fisher Scientific Inc.: R&D Expenditure, 2017-2019
Figure 13.75:    Thermo Fisher Scientific Inc.: SWOT Analysis
Figure 13.76:    Zymo Research Corporation: Product Portfolio
Figure 13.77:    Zymo Research Corporation: SWOT Analysis